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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARFGAP3
All Species:
1.21
Human Site:
S355
Identified Species:
2.96
UniProt:
Q9NP61
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.56
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP61
NP_001135765.1
516
56928
S355
S
Y
F
T
S
S
S
S
Y
F
D
E
P
V
E
Chimpanzee
Pan troglodytes
XP_001171224
516
56901
R355
S
Y
F
T
S
S
S
R
Y
F
D
E
P
V
E
Rhesus Macaque
Macaca mulatta
XP_001107803
516
56806
R355
S
Y
F
T
S
S
S
R
Y
F
D
E
A
V
E
Dog
Lupus familis
XP_848847
517
57143
R356
S
Y
F
T
S
S
S
R
Y
L
D
E
P
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8S3
523
57437
R362
K
W
S
E
Q
S
S
R
Y
F
D
D
P
M
E
Rat
Rattus norvegicus
Q4KLN7
525
57652
R364
W
S
E
Q
S
S
S
R
Y
F
D
D
P
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512573
489
53316
P330
G
S
R
Y
F
E
D
P
T
E
M
R
S
S
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001032507
536
58567
T374
K
Y
K
D
N
P
F
T
S
G
D
S
F
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09531
529
57893
D367
K
S
T
N
N
E
D
D
F
F
S
K
D
Y
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82171
395
43079
R237
A
R
S
S
F
S
S
R
F
D
Y
A
D
N
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
96.7
88.7
N.A.
80.5
80.3
N.A.
62
N.A.
N.A.
56.5
N.A.
N.A.
N.A.
35.1
N.A.
Protein Similarity:
100
96.3
98.2
94.1
N.A.
88.9
87.8
N.A.
73.8
N.A.
N.A.
71
N.A.
N.A.
N.A.
54.6
N.A.
P-Site Identity:
100
93.3
86.6
80
N.A.
46.6
53.3
N.A.
0
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
93.3
86.6
86.6
N.A.
66.6
66.6
N.A.
0
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
20
10
0
10
70
20
20
0
0
% D
% Glu:
0
0
10
10
0
20
0
0
0
10
0
40
0
0
60
% E
% Phe:
0
0
40
0
20
0
10
0
20
60
0
0
10
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
30
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
30
0
% M
% Asn:
0
0
0
10
20
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
10
0
10
0
0
0
0
50
0
10
% P
% Gln:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
10
0
0
0
0
60
0
0
0
10
0
0
0
% R
% Ser:
40
30
20
10
50
70
70
10
10
0
10
10
10
10
10
% S
% Thr:
0
0
10
40
0
0
0
10
10
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
10
% V
% Trp:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
0
10
0
0
0
0
60
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _